A deeper look into translation initiation
Name:
Publisher version
UMass Chan Affiliations
Department of Biochemistry and Molecular PharmacologyRNA Therapeutics Institute
Document Type
Journal ArticlePublication Date
2014-10-23Keywords
Biochemistry, Biophysics, and Structural BiologyCell and Developmental Biology
Genetics and Genomics
Therapeutics
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Show full item recordAbstract
Eukaryotic translation initiation requires coordinated assembly of a remarkable array of initiation factors onto the small ribosomal subunit to select an appropriate mRNA start codon. Studies from Erzberger et al. and Hussain et al. bring new insights into this mechanism by looking at early and late initiation intermediates.Source
Cell. 2014 Oct 23;159(3):475-6. doi: 10.1016/j.cell.2014.10.005. Link to article on publisher's site