Heterogeneity and hypothesis testing in neuropsychiatric illness

Authors
Deutsch, Curtis K.
Ludwig, Wesley W.
McIlvane, William J.
UMass Chan Affiliations
Shriver Center
Document Type
Journal Article
Publication Date
2008-06-26
Keywords
Genetic Heterogeneity
Neuropsychiatry
Neuropsychological Tests
Mental and Social Health
Neuroscience and Neurobiology
Psychiatry and Psychology

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Link to Full Text
http://dx.doi.org/10.1017/S0140525X08004275
Abstract
The confounding effects of heterogeneity in biological psychiatry and psychiatric genetics have been widely discussed in the literature. We suggest an approach in which heterogeneity may be put to use in hypothesis testing, and may find application in evaluation of the Crespi & Badcock (C&B) imprinting hypothesis. Here we consider three potential sources of etiologic subtypes for analysis.
Source
Deutsch, C. K., Ludwig, W. W., & McIlvane, W. J. (2008). Heterogeneity and hypothesis testing in neuropsychiatric illness. Behavioral and Brain Sciences, 31, 266-267. DOI: 10.1017/S0140525X08004275
DOI
10.1017/S0140525X08004275
Permanent Link to this Item
http://hdl.handle.net/20.500.14038/48965
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