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dc.contributor.advisorRobert J. Goldberg
dc.contributor.authorWebster, Kristy T.
dc.contributor.authorJoffe, Samuel W.
dc.contributor.authorMcManus, David D.
dc.contributor.authorKiernan, MIchael S.
dc.contributor.authorLessard, Darleen M.
dc.contributor.authorYarzebski, Jorge L.
dc.contributor.authorDarling, Chad E.
dc.contributor.authorGore, Joel M.
dc.contributor.authorGoldberg, Robert J.
dc.date2022-08-11T08:10:55.000
dc.date.accessioned2022-08-23T17:24:32Z
dc.date.available2022-08-23T17:24:32Z
dc.date.issued2013-05-01
dc.date.submitted2013-05-14
dc.identifier.doi10.13028/1ny4-9513
dc.identifier.urihttp://hdl.handle.net/20.500.14038/49211
dc.description<p>Medical student Kristy Webster participated in this study as part of the Senior Scholars research program at the University of Massachusetts Medical School.</p>
dc.description.abstractBackground: Heart failure is a highly prevalent, morbid, and costly disease with a poor long-term prognosis. Evidence-based therapies utilized over the past 2 decades hold the promise of improved outcomes, yet few contemporary studies have examined survival trends in patients with acute heart failure. Objectives: The primary objective of this population-based study was to describe trends in short and long-term survival in patients hospitalized with acute decompensated heart failure (ADHF). A secondary objective was to examine patient characteristics associated with decreased long-term survival. Methods and Results: We reviewed the medical records of 9,748 patients hospitalized with ADHF at all 11 medical centers in central Massachusetts during 1995, 2000, 2002, and 2004. Patients hospitalized with ADHF were more likely to be elderly and to have been diagnosed with multiple comorbidities in 2004 compared with 1995. Over this period, survival was significantly improved in-hospital, and at 1, 2, and 5 years post-discharge. Five-year survival rates increased from 20% in 1995 to 28% in 2004. Although survival improved substantially over time, older patients and patients with chronic kidney disease, chronic obstructive pulmonary disease, anemia, low body mass index, and low blood pressures had consistently lower post-discharge survival rates than patients without these comorbidities. Conclusion: Between 1995 and 2004, patients hospitalized with ADHF have become older and increasingly comorbid. Although there has been a significant improvement in survival among these patients, their long-term prognosis remains poor, as fewer than 1 in 3 patients hospitalized with ADHF in 2004 survived more than 5 years.
dc.language.isoen_US
dc.rightsCopyright is held by the author(s), with all rights reserved.
dc.subjectHeart Failure
dc.subjectSurvival Rate
dc.subjectOutcome Assessment (Health Care)
dc.subjectCardiovascular Diseases
dc.subjectClinical Epidemiology
dc.subjectHealth Services Research
dc.titleImproved Survival after Heart Failure: A Community-based Perspective
dc.typePoster
dc.identifier.legacyfulltexthttps://escholarship.umassmed.edu/cgi/viewcontent.cgi?article=1150&amp;context=ssp&amp;unstamped=1
dc.identifier.legacycoverpagehttps://escholarship.umassmed.edu/ssp/149
dc.identifier.contextkey4140364
refterms.dateFOA2022-08-28T03:49:40Z
html.description.abstract<p><strong>Background:</strong> Heart failure is a highly prevalent, morbid, and costly disease with a poor long-term prognosis. Evidence-based therapies utilized over the past 2 decades hold the promise of improved outcomes, yet few contemporary studies have examined survival trends in patients with acute heart failure.</p> <p><strong>Objectives:</strong> The primary objective of this population-based study was to describe trends in short and long-term survival in patients hospitalized with acute decompensated heart failure (ADHF). A secondary objective was to examine patient characteristics associated with decreased long-term survival.</p> <p><strong>Methods and Results:</strong> We reviewed the medical records of 9,748 patients hospitalized with ADHF at all 11 medical centers in central Massachusetts during 1995, 2000, 2002, and 2004. Patients hospitalized with ADHF were more likely to be elderly and to have been diagnosed with multiple comorbidities in 2004 compared with 1995. Over this period, survival was significantly improved in-hospital, and at 1, 2, and 5 years post-discharge. Five-year survival rates increased from 20% in 1995 to 28% in 2004. Although survival improved substantially over time, older patients and patients with chronic kidney disease, chronic obstructive pulmonary disease, anemia, low body mass index, and low blood pressures had consistently lower post-discharge survival rates than patients without these comorbidities.</p> <p><strong>Conclusion:</strong> Between 1995 and 2004, patients hospitalized with ADHF have become older and increasingly comorbid. Although there has been a significant improvement in survival among these patients, their long-term prognosis remains poor, as fewer than 1 in 3 patients hospitalized with ADHF in 2004 survived more than 5 years.</p>
dc.identifier.submissionpathssp/149
dc.contributor.departmentMeyers Primary Care Institute
dc.contributor.departmentDepartment of Emergency Medicine
dc.contributor.departmentDepartment of Quantitative Health Sciences
dc.contributor.departmentDepartment of Medicine, Division of Cardiovascular Medicine


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