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    The use of acellular dermal regeneration template for recalcitrant pilonidal disease

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    Authors
    Vaughn, Carolyn J.
    Lalikos, Janice F.
    Faculty Advisor
    Janice Lalikos
    UMass Chan Affiliations
    Department of Surgery, Division of Plastic Surgery
    Document Type
    Journal Article
    Publication Date
    2011-06-01
    Keywords
    Adult
    Chondroitin Sulfates
    Collagen
    Debridement
    Female
    Humans
    Male
    *Negative-Pressure Wound Therapy
    Pilonidal Sinus
    Recurrence
    *Skin, Artificial
    Wound Healing
    Dermatology
    Plastic Surgery
    Skin and Connective Tissue Diseases
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    Link to Full Text
    http://dx.doi.org/10.12968/jowc.2011.20.6.275
    Abstract
    Numerous techniques have been described for the treatment of pilonidal disease, yet there remains no consensus on the optimal management of recurrent pilonidal disease. Pilonidal wounds often lack the structural integrity to heal over and Integra provides a scaffold for the regrowth of an autogenous dermis from the patient's own fibroblasts and collagen. Postoperative negative pressure wound therapy (NPWT) may speed vascularisation of Integra, re-epithelialisation, and wound closure. This case report concerns two patients with chronic pilonidal sinuses who underwent wide excision and placement of Integra with postoperative NPWT. Postoperatively, the patients were assessed for complications and recurrence. Both patients went on to heal and did not require further surgical treatment after a median follow-up of 29 months. Integra may help prevent pocket or cyst formation during the closure process and provides a neodermis, allowing for full re-epithelialisation. More research and a longer follow-up are needed to evaluate the role of Integra and NPWT in recurrent pilonidal disease.
    Source
    J Wound Care. 2011 Jun;20(6):275-7. Link to article on publisher's site
    DOI
    10.12968/jowc.2011.20.6.275
    Permanent Link to this Item
    http://hdl.handle.net/20.500.14038/49252
    PubMed ID
    21727876
    Notes

    Medical student Carolyn Vaughn participated in this study as part of the Senior Scholars research program at the University of Massachusetts Medical School.

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    Link to Article in PubMed
    ae974a485f413a2113503eed53cd6c53
    10.12968/jowc.2011.20.6.275
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    T.H. Chan School of Medicine Student Publications
    Senior Scholars Program

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