The use of acellular dermal regeneration template for recalcitrant pilonidal disease
Faculty Advisor
Janice LalikosUMass Chan Affiliations
Department of Surgery, Division of Plastic SurgeryDocument Type
Journal ArticlePublication Date
2011-06-01Keywords
AdultChondroitin Sulfates
Collagen
Debridement
Female
Humans
Male
*Negative-Pressure Wound Therapy
Pilonidal Sinus
Recurrence
*Skin, Artificial
Wound Healing
Dermatology
Plastic Surgery
Skin and Connective Tissue Diseases
Metadata
Show full item recordAbstract
Numerous techniques have been described for the treatment of pilonidal disease, yet there remains no consensus on the optimal management of recurrent pilonidal disease. Pilonidal wounds often lack the structural integrity to heal over and Integra provides a scaffold for the regrowth of an autogenous dermis from the patient's own fibroblasts and collagen. Postoperative negative pressure wound therapy (NPWT) may speed vascularisation of Integra, re-epithelialisation, and wound closure. This case report concerns two patients with chronic pilonidal sinuses who underwent wide excision and placement of Integra with postoperative NPWT. Postoperatively, the patients were assessed for complications and recurrence. Both patients went on to heal and did not require further surgical treatment after a median follow-up of 29 months. Integra may help prevent pocket or cyst formation during the closure process and provides a neodermis, allowing for full re-epithelialisation. More research and a longer follow-up are needed to evaluate the role of Integra and NPWT in recurrent pilonidal disease.Source
J Wound Care. 2011 Jun;20(6):275-7. Link to article on publisher's siteDOI
10.12968/jowc.2011.20.6.275Permanent Link to this Item
http://hdl.handle.net/20.500.14038/49252PubMed ID
21727876Notes
Medical student Carolyn Vaughn participated in this study as part of the Senior Scholars research program at the University of Massachusetts Medical School.
Related Resources
Link to Article in PubMedae974a485f413a2113503eed53cd6c53
10.12968/jowc.2011.20.6.275