Survey of breast-feeding practices and outcomes in the cystic fibrosis population
UMass Chan Affiliations
Department of PediatricsDocument Type
Journal ArticlePublication Date
2004-03-17Keywords
AdolescentAdult
Anti-Bacterial Agents
Breast Feeding
Child
Child, Preschool
Cystic Fibrosis
Drug Utilization
Forced Expiratory Volume
Humans
Infant
Infant Formula
Outcome Assessment (Health Care)
Questionnaires
Severity of Illness Index
Time Factors
Life Sciences
Medicine and Health Sciences
Metadata
Show full item recordAbstract
The aim of this study was to survey cystic fibrosis (CF) patients to determine the frequency of breast-feeding and its association with onset and severity of CF symptoms. Three thousand, two hundred questionnaires were sent to 30 accredited CF centers for anonymous completion. Eight hundred and sixty-three questionnaires were returned and scanned into a database. All results were adjusted for age at time of filling out the questionnaire. Age at onset of symptoms, percent forced expired volume in 1 sec (FEV1%) predicted, and intravenous (IV) antibiotic use were analyzed based on breast-feeding history. Approximately 49% of respondents received human breast milk at some time, but only 18% were exclusively breast-fed. Breast-feeding exclusively for greater than 6 months was associated with a decrease in disease severity based on recent intravenous antibiotic use compared to no breast-feeding (P = 0.03). There was no statistically significant change in onset of symptoms in the setting of breast-feeding; however, a trend toward delayed onset was seen in those receiving human milk. Fifty-three percent of those who breast-fed exclusively > or = 6 months had FEV1% values > 90%, compared to 47% of those not breast-fed. This is a suggestive but not statistically significant difference. In conclusion, breast-feeding for > or = 6 months is associated with decreased use of intravenous antibiotics in the 2 years prior to administering the questionnaire. This survey indicates that breast-feeding is not harmful to children with CF, and may be beneficial.Source
Pediatr Pulmonol. 2004 Apr;37(4):362-7. Link to article on publisher's siteDOI
10.1002/ppul.10450Permanent Link to this Item
http://hdl.handle.net/20.500.14038/49436PubMed ID
15022134Notes
Medical student Eliza Parker participated in this study as part of the Senior Scholars research program.Related Resources
Link to Article in PubMedae974a485f413a2113503eed53cd6c53
10.1002/ppul.10450