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    Regulation of specific genes during the cell cycle. Utilization of homologous cDNAs and cloned sequences for studying histone gene expression in human cells

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    Authors
    Stein, Gary S.
    Stein, Janet L.
    Marashi, Farhad
    Parker, M. I.
    Sierra, L. F.
    UMass Chan Affiliations
    Department of Cell Biology
    Document Type
    Journal Article
    Publication Date
    1980-12-01
    Keywords
    Base Sequence
    *Cell Cycle
    Chromosomal Proteins, Non-Histone
    Cloning, Molecular
    *Gene Expression Regulation
    Histones
    Humans
    Interphase
    Models, Genetic
    Nucleic Acid Hybridization
    RNA, Messenger
    Transcription, Genetic
    Cell Biology
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    Link to Full Text
    http://dx.doi.org/10.1007/BF02785095
    Abstract
    Evidence for differential gene expression during the cell cycle and approaches for studying cell-cycle-stage specific gene expression are summarized. Attention is focused on regulation of histone gene expression during the cell cycle of continuously dividing cells and after stimulation of nondividing cells to proliferate. The level(s) at which control of histone gene expression occurs and the possible involvement of chromosomal proteins in the regulation of histone gene expression are discussed. The preparation of cloned human histone sequences and their use in studying the structural and functional properties of human histone genes are presented. Index Entries: Cell cycle, gene regulation during; gene regulation, during the cell cycle; regulation of specific genes, during the cell cycle; DNAs, homologous, and histone gene expression; cloned DNAs, and histone gene expression; histone gene expression; gene expression, histone; cloned human histone sequences.
    Source
    Cell Biophys. 1980 Dec;2(4):291-314. Link to article on publisher's site
    DOI
    10.1007/BF02785095
    Permanent Link to this Item
    http://hdl.handle.net/20.500.14038/49507
    PubMed ID
    6163542
    Related Resources
    Link to Article in PubMed
    ae974a485f413a2113503eed53cd6c53
    10.1007/BF02785095
    Scopus Count
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