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    Nonhistone chromosomal protein synthesis: utilization of preexisting and newly transcribed messenger RNA's

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    Authors
    Stein, Gary S.
    Matthews, David E.
    UMass Chan Affiliations
    Department of Cell Biology
    Document Type
    Journal Article
    Publication Date
    1973-07-06
    Keywords
    Chromatin
    Chromosomes
    Dactinomycin
    Electrophoresis, Polyacrylamide Gel
    Female
    Hela Cells
    Humans
    Mitosis
    Nucleoproteins
    RNA, Messenger
    Templates, Genetic
    Transcription, Genetic
    Tritium
    Tryptophan
    Cell Biology
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    Link to Full Text
    http://dx.doi.org/10.1126/science.181.4094.71
    Abstract
    Treatment of HeLa S(3) cells with actinomycin D during mitosis suppresses the synthesis of several major classes of nonhistone chromosomal proteins during the subsequent period before DNA replication, but allows the synthesis of other species of these proteins. Such results are consistent with the utilization of preexisting, as well as newly transcribed, messenger RNA's for nonhistone chromosomal protein synthesis during the prereplicative phase of the cell cycle.
    Source
    Science. 1973 Jul 6;181(94):71-3.
    Permanent Link to this Item
    http://hdl.handle.net/20.500.14038/49560
    PubMed ID
    4714292
    Related Resources
    Link to Article in PubMed
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    UMass Chan Faculty and Researcher Publications

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