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    Comparison of Right Lobe Donor Hepatectomy with Elective Right Hepatectomy for Other Causes in New York

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    Authors
    Burr, Andrew T.
    Csikesz, Nicholas G.
    Gonzales, Earl
    Tseng, Jennifer F.
    Saidi, Reza F.
    Bozorgzadeh, Adel
    Shah, Shimul A.
    UMass Chan Affiliations
    Department of Surgery
    Document Type
    Journal Article
    Publication Date
    2011-06-01
    Keywords
    Hepatectomy
    Tissue Donors
    Liver Transplantation
    Surgery
    
    Metadata
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    Link to Full Text
    http://dx.doi.org/10.1007/s10620-010-1489-6
    Abstract
    INTRODUCTION: Right lobe donor hepatectomy (RLDH) is a potential source of liver allografts given the ongoing shortage of deceased donor organs available. Since there is no live donor registry in the United States, a population-based, unsolicited state-wide analysis has yet to be reported. METHODS: The New York (NY) State Inpatient Database was used to query 1,524 elective liver lobectomies performed from 2001 to 2006. RLDH were identified in this cohort (n = 195; 13%). Most common indications for elective right lobe hepatectomy (ERH) were metastatic colon cancer (50%) and hepatocellular carcinoma (HCC) (34%). Primary outcomes were mortality, perioperative resources and major postoperative complications. RESULTS: After a dramatic drop in 2002, there was a slow increase in RLDH from 2003 to 2006 in New York. Donors were younger (median age 36 vs. 60 years, P < 0.0001) and healthier (75% with no comorbidities vs. 18%, P < 0.0001) than patients undergoing ERH for other causes. Median length of hospital stay was 7 days in both groups. Donors were less likely to require blood transfusion (22.6 vs. 62.8%, P < 0.0001) and received less blood (mean 0.10 units vs. 2.4 units). Major post-operative complications based on the Clavien classification occurred in only 2.6% of donor cases compared to 13.8% in non-donors (P < 0.0001). There was one RLDH in-hospital mortality (0.5%) in New York compared to 4.3% after ERH (P = 0.003). CONCLUSIONS: This study represents one of the first unsolicited regional analyses of donor morbidity and resource utilization for RLDH and further emphasizes the need and utility of a live donor registry.
    Source
    Dig Dis Sci. 2011 Jun;56(6):1869-75. Epub 2010 Nov 27. Link to article on publisher's site
    DOI
    10.1007/s10620-010-1489-6
    Permanent Link to this Item
    http://hdl.handle.net/20.500.14038/49808
    PubMed ID
    21113662
    Related Resources
    Link to Article in PubMed
    ae974a485f413a2113503eed53cd6c53
    10.1007/s10620-010-1489-6
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