UMass Chan AffiliationsDepartment of Biochemistry and Molecular Pharmacology
Program in Systems Biology
Document TypeJournal Article
MetadataShow full item record
AbstractChIP is a powerful method for analyzing protein-DNA interactions that occur in vivo. A basic protocol involves immunoprecipitation of the cross-linked nucleoprotein complex and isolating and analyzing the DNA that is associated with the protein of interest. The antibody and chromatin amounts indicated here are for ChIP-chip and ChIP-seq and are approximately 10-fold higher than for a standard ChIP assay.
Cold Spring Harb Protoc. 2018 Apr 2;2018(4):pdb.prot082610. doi: 10.1101/pdb.prot082610. Link to article on publisher's site
Permanent Link to this Itemhttp://hdl.handle.net/20.500.14038/49860