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    A chloroacetamidine-based inactivator of protein arginine methyltransferase 1: design, synthesis, and in vitro and in vivo evaluation

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    Authors
    Obianyo, Obiamaka
    Causey, Corey P.
    Osborne, Tanesha C.
    Jones, Justin E.
    Lee, Young-Ho
    Stallcup, Michael R.
    Thompson, Paul R
    UMass Chan Affiliations
    Department of Biochemistry and Molecular Pharmacology
    Document Type
    Journal Article
    Publication Date
    2010-06-14
    Keywords
    Amidines
    Arginine
    Catalytic Domain
    Cell Line
    Enzyme Inhibitors
    Humans
    Methylation
    Peptides
    Protein-Arginine N-Methyltransferases
    Cl-amidine
    enzymes
    inhibitors
    protein arginine methyltransferase
    transcription
    Biochemistry
    Enzymes and Coenzymes
    Medicinal-Pharmaceutical Chemistry
    Therapeutics
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    Metadata
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    Link to Full Text
    http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3060404/
    Source
    Chembiochem. 2010 Jun 14;11(9):1219-23. doi: 10.1002/cbic.201000209. Link to article on publisher's site
    DOI
    10.1002/cbic.201000209
    Permanent Link to this Item
    http://hdl.handle.net/20.500.14038/50051
    Notes

    At the time of publication, Paul Thompson was not yet affiliated with UMass Medical School.

    Related Resources
    Link to Article in PubMed
    ae974a485f413a2113503eed53cd6c53
    10.1002/cbic.201000209
    Scopus Count
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