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dc.contributor.authorBostrom, John A.
dc.contributor.authorSaczynski, Jane S.
dc.contributor.authorHajduk, Alexandra M.
dc.contributor.authorDonahue, Kevin
dc.contributor.authorRosenthal, Lawrence S.
dc.contributor.authorBrowning, Clifford
dc.contributor.authorEnnis, Cynthia
dc.contributor.authorFloyd, Kevin C.
dc.contributor.authorRichardson, Heather
dc.contributor.authorEsa, Nada
dc.contributor.authorOgarek, Jessica
dc.contributor.authorMcManus, David D.
dc.date2022-08-11T08:11:02.000
dc.date.accessioned2022-08-23T17:29:18Z
dc.date.available2022-08-23T17:29:18Z
dc.date.issued2017-06-01
dc.date.submitted2017-06-01
dc.identifier.citationCrit Pathw Cardiol. 2017 Jun;16(2):71-75. doi: 10.1097/HPC.0000000000000101. <a href="https://doi.org/10.1097/HPC.0000000000000101">Link to article on publisher's site</a>
dc.identifier.issn1535-2811 (Linking)
dc.identifier.doi10.1097/HPC.0000000000000101
dc.identifier.pmid28509707
dc.identifier.urihttp://hdl.handle.net/20.500.14038/50286
dc.description<p>John Bostrom is a medical student at the University of Massachusetts Medical School.</p>
dc.description.abstractBACKGROUND: Impairments in psychosocial status and cognition relate to poor clinical outcomes in patients with atrial fibrillation (AF). However, how often these conditions co-occur and associations between burden of psychosocial and cognitive impairment and quality of life (QoL) have not been systematically examined in patients with AF. METHODS: A total of 218 patients with symptomatic AF were enrolled in a prospective study of AF and psychosocial factors between May 2013 and October 2014 at the University of Massachusetts Medical Center. Cognitive function, depression, and anxiety were assessed at baseline and AF-specific QoL was assessed 6 months after enrollment using validated instruments. Demographic and clinical information were obtained from a structured interview and medical record review. RESULTS: The mean age of the study participants was 63.5 +/- 10.2 years, 35% were male, and 81% had paroxysmal AF. Prevalences of impairment in 1, 2, and 3 psychosocial/cognitive domains (eg, depression, anxiety, or cognition) were 75 (34.4%), 51 (23.4%), and 16 (7.3%), respectively. Patients with co-occurring psychosocial/cognitive impairments (eg, > 1 domain) were older, more likely to smoke, had less education, and were more likely to have heart failure (all P < 0.05). Compared with participants with no psychosocial/cognitive impairments, AF-specific QoL at 6 months was significantly poorer among participants with baseline impairment in 2 (B = -13.6, 95% CI: -21.7 to -5.4) or 3 (B = -15.1, 95% CI: -28.0 to -2.2) psychosocial/cognitive domains. CONCLUSION: Depression, anxiety, and impaired cognition were common in our cohort of patients with symptomatic AF and often co-occurred. Higher burden of psychosocial/cognitive impairment was associated with poorer AF-specific QoL.
dc.language.isoen_US
dc.relation<a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&list_uids=28509707&dopt=Abstract">Link to Article in PubMed</a>
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subjectUMCCTS funding
dc.subjectCardiology
dc.subjectCardiovascular Diseases
dc.subjectMental and Social Health
dc.subjectPsychiatry and Psychology
dc.subjectTranslational Medical Research
dc.titleBurden of Psychosocial and Cognitive Impairment in Patients With Atrial Fibrillation
dc.typeJournal Article
dc.source.journaltitleCritical pathways in cardiology
dc.source.volume16
dc.source.issue2
dc.identifier.legacyfulltexthttps://escholarship.umassmed.edu/cgi/viewcontent.cgi?article=1115&amp;context=umccts_pubs&amp;unstamped=1
dc.identifier.legacycoverpagehttps://escholarship.umassmed.edu/umccts_pubs/115
dc.identifier.contextkey10236315
refterms.dateFOA2022-08-23T17:29:18Z
html.description.abstract<p>BACKGROUND: Impairments in psychosocial status and cognition relate to poor clinical outcomes in patients with atrial fibrillation (AF). However, how often these conditions co-occur and associations between burden of psychosocial and cognitive impairment and quality of life (QoL) have not been systematically examined in patients with AF.</p> <p>METHODS: A total of 218 patients with symptomatic AF were enrolled in a prospective study of AF and psychosocial factors between May 2013 and October 2014 at the University of Massachusetts Medical Center. Cognitive function, depression, and anxiety were assessed at baseline and AF-specific QoL was assessed 6 months after enrollment using validated instruments. Demographic and clinical information were obtained from a structured interview and medical record review.</p> <p>RESULTS: The mean age of the study participants was 63.5 +/- 10.2 years, 35% were male, and 81% had paroxysmal AF. Prevalences of impairment in 1, 2, and 3 psychosocial/cognitive domains (eg, depression, anxiety, or cognition) were 75 (34.4%), 51 (23.4%), and 16 (7.3%), respectively. Patients with co-occurring psychosocial/cognitive impairments (eg, > 1 domain) were older, more likely to smoke, had less education, and were more likely to have heart failure (all P < 0.05). Compared with participants with no psychosocial/cognitive impairments, AF-specific QoL at 6 months was significantly poorer among participants with baseline impairment in 2 (B = -13.6, 95% CI: -21.7 to -5.4) or 3 (B = -15.1, 95% CI: -28.0 to -2.2) psychosocial/cognitive domains.</p> <p>CONCLUSION: Depression, anxiety, and impaired cognition were common in our cohort of patients with symptomatic AF and often co-occurred. Higher burden of psychosocial/cognitive impairment was associated with poorer AF-specific QoL.</p>
dc.identifier.submissionpathumccts_pubs/115
dc.contributor.departmentDepartment of Medicine, Division of Cardiovascular Medicine
dc.contributor.departmentSchool of Medicine
dc.source.pages71-75


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