UMass Chan Affiliations
Department of Medicine, Division of Hematology/OncologyDocument Type
Journal ArticlePublication Date
1988-01-01Keywords
ElectrocardiographyFluorouracil
Heart
Humans
Male
Middle Aged
Life Sciences
Medicine and Health Sciences
Women's Studies
Metadata
Show full item recordAbstract
Cardiotoxicity manifested as myocardial ischemia is not generally recognized as a side effect of 5-fluorouracil. However, there have been at least 35 cases reported since 1975. In only one of these cases was a somewhat detailed evaluation done to rule out underlying coronary disease. The case reported here of 5-FU cardiotoxicity included an extensive cardiac evaluation to rule out underlying coronary disease and to assess spasm. The literature on 5-FU cardiotoxicity is also reviewed, and its possible mechanisms are analyzed.Source
Cancer. 1988 Jan 1;61(1):36-45.
DOI
10.1002/1097-0142(19880101)61:1<36::AID-CNCR2820610108>3.0.CO;2-6Permanent Link to this Item
http://hdl.handle.net/20.500.14038/50594PubMed ID
3275485Related Resources
ae974a485f413a2113503eed53cd6c53
10.1002/1097-0142(19880101)61:1<36::AID-CNCR2820610108>3.0.CO;2-6