Ialpha exon-replacement mice synthesize a spliced HPRT-C(alpha) transcript which may explain their ability to switch to IgA. Inhibition of switching to IgG in these mice
UMass Chan Affiliations
Department of Molecular Genetics and MicrobiologyDocument Type
Journal ArticlePublication Date
1999-01-01Keywords
AnimalsExons
Gene Expression Regulation
Germ Cells
Hypoxanthine Phosphoribosyltransferase
Immunoglobulin A
*Immunoglobulin Class Switching
Immunoglobulin G
Immunoglobulin Heavy Chains
Mice
Mice, Knockout
*RNA Splicing
Recombination, Genetic
Sequence Analysis, DNA
Life Sciences
Medicine and Health Sciences
Women's Studies