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Cytoskeleton--plasma membrane interactions

dc.contributor.authorLuna, Elizabeth J.
dc.contributor.authorHitt, Anne L.
dc.date2022-08-11T08:11:04.000
dc.date.accessioned2022-08-23T17:31:30Z
dc.date.available2022-08-23T17:31:30Z
dc.date.issued1992-11-06
dc.date.submitted2007-11-13
dc.identifier.citationScience. 1992 Nov 6;258(5084):955-64.
dc.identifier.issn0036-8075 (Print)
dc.identifier.pmid1439807
dc.identifier.urihttp://hdl.handle.net/20.500.14038/50750
dc.description.abstractProteins at the boundary between the cytoskeleton and the plasma membrane control cell shape, delimit specialized membrane domains, and stabilize attachments to other cells and to the substrate. These proteins also regulate cell locomotion and cytoplasmic responses to growth factors and other external stimuli. This diversity of cellular functions is matched by the large number of biochemical mechanisms that mediate the connections between membrane proteins and the underlying cytoskeleton, the so-called membrane skeleton. General organizational themes are beginning to emerge from examination of this biochemical diversity.
dc.language.isoen_US
dc.relation<a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=1439807&dopt=Abstract">Link to article in PubMed</a>
dc.relation.urlhttp://www.sciencemag.org/content/258/5084/955.full.pdf
dc.subjectCell Adhesion
dc.subjectCell Membrane
dc.subjectCell Movement
dc.subjectCell Physiology
dc.subjectCells
dc.subjectCytoskeleton
dc.subjectHomeostasis
dc.subjectHumans
dc.subjectCell Biology
dc.subjectLife Sciences
dc.subjectMedicine and Health Sciences
dc.titleCytoskeleton--plasma membrane interactions
dc.typeJournal Article
dc.source.journaltitleScience (New York, N.Y.)
dc.source.volume258
dc.source.issue5084
dc.identifier.legacycoverpagehttps://escholarship.umassmed.edu/wfc_pp/279
dc.identifier.contextkey392363
html.description.abstract<p>Proteins at the boundary between the cytoskeleton and the plasma membrane control cell shape, delimit specialized membrane domains, and stabilize attachments to other cells and to the substrate. These proteins also regulate cell locomotion and cytoplasmic responses to growth factors and other external stimuli. This diversity of cellular functions is matched by the large number of biochemical mechanisms that mediate the connections between membrane proteins and the underlying cytoskeleton, the so-called membrane skeleton. General organizational themes are beginning to emerge from examination of this biochemical diversity.</p>
dc.identifier.submissionpathwfc_pp/279
dc.contributor.departmentDepartment of Cell Biology
dc.source.pages955-64


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