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    Comparison of patterns of smoking behavior change among smokers in the Multiple Risk Factor Intervention Trial (MRFIT)

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    Authors
    Ockene, Judith K.
    Hymowitz, Norman
    Sexton, Mary
    Broste, Steven K.
    UMass Chan Affiliations
    Department of Medicine, Division of Preventive and Behavioral Medicine
    Document Type
    Journal Article
    Publication Date
    1982-11-01
    Keywords
    Adult
    Behavior
    Clinical Trials as Topic
    Heart Diseases
    Humans
    Male
    Middle Aged
    Risk
    *Smoking
    Thiocyanates
    Life Sciences
    Medicine and Health Sciences
    Women's Studies
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    Link to Full Text
    http://dx.doi.org/10.1016/0091-7435(82)90025-1
    Abstract
    The Multiple Risk Factor Intervention Trial (MRFIT) is a 6-year clinical trial for the study of the prevention of heart disease. Twelve thousand eight hundred and sixty-six men in the upper 10–15% of heart attack risk were randomly assigned to Special Intervention (SI) or Usual Care (UC). The SI participants received “risk factor” (hypertension, hypercholesterolemia, and cigarette smoking) intervention at the clinical centers; the UC participants were referred to their usual source of medical care for treatment. Forty percent of SI and 21% of UC smokers at entry reported not smoking at year 4, with lighter smokers in both treatment groups reporting significantly more cessation than heavier smokers. The greatest SI-UC difference in cessation rate was achieved during the first year of the program. The use of serum thiocyanate, an objective indicator of cigarette smoking, avoided problems inherent in self-reported data. Misreporting of smoking status was found in both groups with more occurring among the SI smokers. Cohort analysis revealed that of the smokers who stopped during the first year of the trial, 68% of SI and 57% of UC remained abstinent through the 4-year follow-up. Of the smokers who stopped later in the program the UC had better maintenance rates than the SI.
    Source

    Prev Med. 1982 Nov;11(6):621-38.

    DOI
    10.1016/0091-7435(82)90025-1
    Permanent Link to this Item
    http://hdl.handle.net/20.500.14038/50813
    PubMed ID
    6761682
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    Link to article in PubMed

    ae974a485f413a2113503eed53cd6c53
    10.1016/0091-7435(82)90025-1
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