The multiple risk factor intervention trial (MRFIT). V. Intervention on smoking
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UMass Chan Affiliations
Department of Medicine, Division of Preventive and Behavioral MedicineDocument Type
Journal ArticlePublication Date
1981-07-01Keywords
Adult*Behavior Therapy
Clinical Trials as Topic
Coronary Disease
Follow-Up Studies
*Health Status Indicators
*Health Surveys
Humans
Male
Middle Aged
Patient Compliance
Patient Education as Topic
Smoking
Thiocyanates
Time Factors
Life Sciences
Medicine and Health Sciences
Women's Studies
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Show full item recordAbstract
The development, implementation, and results of the smoking cessation program of the Multiple Risk Factor Intervention Trial (MRFIT) are presented. The MRFIT is a 6-year clinical trial designed to investigate the effects of reducing cardiovascular risk factors -- elevated cholesterol, hypertension, and cigarette smoking -- in a group of asymptomatic men at high risk of cardiovascular disease. The men participated in an integrated intervention program that offered both group and individual formats, a structured maintenance program for those who stopped smoking, and an extended intervention program for those unable to quit initially. Results among the original 4,103 smokers included a 47.3% quit rate 4 months after program initiation and a 45.9% quit rate after 4 years. Of those reporting no smoking at 4 months, 56% were abstinent at all visits through 48 months. Most recidivism occurred soon after initial cessation, with 17% of the men who reported quitting at 4 months reporting smoking 4 months later. The quit rates were strongly associated with the initial level of smoking, with light smokers reporting higher quit rates and lower recidivism rates at all visits through 4 years. Results exceed trial goals whether measured by self-reports or by thiocyanate levels, an objective assessment of smoking behavior. Discussion focuses on understanding the variables contributing to smoking cessation and to achieving the goals of reduction of risk of cardiovascular disease.Source
Prev Med. 1981 Jul;10(4):476-500.
DOI
10.1016/0091-7435(81)90061-XPermanent Link to this Item
http://hdl.handle.net/20.500.14038/50814PubMed ID
7027239Related Resources
ae974a485f413a2113503eed53cd6c53
10.1016/0091-7435(81)90061-X