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dc.contributor.authorDiFranza, Joseph R.
dc.contributor.authorSavageau, Judith A.
dc.contributor.authorFletcher, Kenneth E.
dc.contributor.authorOckene, Judith K.
dc.contributor.authorRigotti, Nancy A.
dc.contributor.authorMcNeill, Ann D.
dc.contributor.authorColeman, Mardia A.
dc.contributor.authorWood, Constance
dc.date2022-08-11T08:11:05.000
dc.date.accessioned2022-08-23T17:32:07Z
dc.date.available2022-08-23T17:32:07Z
dc.date.issued2004-02-01
dc.date.submitted2008-02-26
dc.identifier.citation<p>Addict Behav. 2004 Feb;29(2):261-72.</p>
dc.identifier.issn0306-4603 (Print)
dc.identifier.doi10.1016/j.addbeh.2003.08.002
dc.identifier.pmid14732415
dc.identifier.urihttp://hdl.handle.net/20.500.14038/50886
dc.description.abstractCONTEXT: It has not been determined if a youth's reaction to the first smoking experience is predictive of future nicotine dependence, or whether the impact of the first cigarette can be altered by manipulating levels of tar, nicotine and menthol. OBJECTIVE: To determine if the recalled response to the first cigarette is predictive of the development of symptoms of nicotine dependence and whether it is influenced by the type of cigarette smoked. DESIGN AND SETTING: A retrospective/prospective longitudinal study of the natural history of nicotine dependence employing individual interviews conducted three times annually in two urban school systems over 3 years. Subjects were asked to recall their first smoking experience. PARTICIPANTS: A cohort of 237 subjects who had inhaled on a cigarette. MAIN OUTCOME MEASURES: Symptoms associated with smoking; the Hooked on Nicotine Checklist of 10 symptoms of dependence. RESULTS: Reactions to the initial smoking experience were unrelated to gender or cigarette brand, strength or mentholation. Relaxation in response to the first inhalation was the strongest predictor of symptoms of nicotine dependence. Dizziness and nausea were also independent predictors of dependence symptoms. CONCLUSIONS: The data suggest that increased sensitivity to nicotine as manifested by relaxation, dizziness, or nausea in response to the first exposure to nicotine represents a risk factor for the development of nicotine dependence.
dc.language.isoen_US
dc.relation<p><a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=14732415&dopt=Abstract ">Link to article in PubMed</a></p>
dc.relation.urlhttp://dx.doi.org/10.1016/j.addbeh.2003.08.002
dc.subjectAdolescent
dc.subjectDizziness
dc.subjectFemale
dc.subjectHumans
dc.subjectMale
dc.subjectMassachusetts
dc.subject*Mental Recall
dc.subjectNausea
dc.subjectPsychometrics
dc.subjectRelaxation
dc.subjectRetrospective Studies
dc.subjectRisk Factors
dc.subjectSmoking
dc.subjectTobacco Use Disorder
dc.subjectLife Sciences
dc.subjectMedicine and Health Sciences
dc.subjectWomen's Studies
dc.titleRecollections and repercussions of the first inhaled cigarette
dc.typeJournal Article
dc.source.journaltitleAddictive behaviors
dc.source.volume29
dc.source.issue2
dc.identifier.legacycoverpagehttps://escholarship.umassmed.edu/wfc_pp/414
dc.identifier.contextkey437170
html.description.abstract<p>CONTEXT: It has not been determined if a youth's reaction to the first smoking experience is predictive of future nicotine dependence, or whether the impact of the first cigarette can be altered by manipulating levels of tar, nicotine and menthol.</p> <p>OBJECTIVE: To determine if the recalled response to the first cigarette is predictive of the development of symptoms of nicotine dependence and whether it is influenced by the type of cigarette smoked.</p> <p>DESIGN AND SETTING: A retrospective/prospective longitudinal study of the natural history of nicotine dependence employing individual interviews conducted three times annually in two urban school systems over 3 years. Subjects were asked to recall their first smoking experience.</p> <p>PARTICIPANTS: A cohort of 237 subjects who had inhaled on a cigarette.</p> <p>MAIN OUTCOME MEASURES: Symptoms associated with smoking; the Hooked on Nicotine Checklist of 10 symptoms of dependence.</p> <p>RESULTS: Reactions to the initial smoking experience were unrelated to gender or cigarette brand, strength or mentholation. Relaxation in response to the first inhalation was the strongest predictor of symptoms of nicotine dependence. Dizziness and nausea were also independent predictors of dependence symptoms.</p> <p>CONCLUSIONS: The data suggest that increased sensitivity to nicotine as manifested by relaxation, dizziness, or nausea in response to the first exposure to nicotine represents a risk factor for the development of nicotine dependence.</p>
dc.identifier.submissionpathwfc_pp/414
dc.contributor.departmentCenter for Health Policy and Research
dc.contributor.departmentDepartment of Medicine, Division of Preventive and Behavioral Medicine
dc.contributor.departmentDepartment of Psychiatry
dc.contributor.departmentDepartment of Family Medicine and Community Health
dc.source.pages261-72


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