Venous thromboembolism risk stratification in trauma using the Caprini risk assessment model
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Jon DorfmanDocument Type
Journal ArticlePublication Date
2021-10-23
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Introduction: The Caprini risk assessment model is widely used for venous thromboembolism (VTE) but has limited data in trauma. The study objective was to determine if the Caprini risk assessment model could effectively risk stratify trauma patients. Materials and methods: We performed a retrospective review of trauma patients aged ≥18 years, admitted for greater than 24 h at a level one trauma center from January 1, 2018, to December 31, 2018. Demographic and clinical data were analyzed to generate Caprini scores. Multiple logistic regression assessed odds of inpatient VTE. Results: A total of 1279 patients met study eligibility, with a total of 33 VTE (2.6%). When comparing those with VTE to those without, the mean age was lower (52.5 vs 59.5, p = 0.06, respectively), sex distribution was similar, but mean body mass index was higher (30.2 vs 27.4, p = 0.019, respectively). The mean Caprini score was 9.9, and 75.5% had a score >4, the traditional Caprini high-risk cutoff. The VTE group had a higher mean Injury Severity Score (17.8 vs 12.6, p = 0.011), and mean Caprini score (16.4 vs 9.8, p < 0.001). Multiple logistic regression found Caprini score, not Injury Severity Score, was associated with higher odds of VTE (adjusted odds ratio 1.06, 95% confidence interval 1.02-1.10), after adjusting for Injury Severity Score, any missed doses of VTE chemoprophylaxis, and VTE prophylaxis type. Conclusions: Higher Caprini scores are associated with elevated odds of inpatient VTE within hospitalized trauma patients. These data support using the Caprini risk assessment model in the trauma population, which may aid in risk stratification.Source
Hazeltine MD, Guber RD, Buettner H, Dorfman JD. Venous thromboembolism risk stratification in trauma using the Caprini risk assessment model. Thromb Res. 2021 Dec;208:52-57. doi: 10.1016/j.thromres.2021.10.016. Epub 2021 Oct 23. PMID: 34715509.DOI
10.1016/j.thromres.2021.10.016Permanent Link to this Item
http://hdl.handle.net/20.500.14038/51249PubMed ID
34715509Notes
Robert Guber participated in this study as a medical student in the Senior Scholars research program at the UMass Chan Medical School.Rights
Copyright © 2021 Elsevier Ltd. All rights reserved.ae974a485f413a2113503eed53cd6c53
10.1016/j.thromres.2021.10.016