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dc.contributor.authorHe, Qian
dc.contributor.authorLiu, Shuying
dc.contributor.authorLiang, Zhenglun
dc.contributor.authorLu, Shan
dc.contributor.authorCun, Wei
dc.contributor.authorMao, Qunyan
dc.date.accessioned2022-12-09T19:52:20Z
dc.date.available2022-12-09T19:52:20Z
dc.date.issued2022-11-25
dc.identifier.citationHe Q, Liu S, Liang Z, Lu S, Cun W, Mao Q. Mouse Study of Combined DNA/Protein COVID-19 Vaccine to Boost High Levels of Antibody and Cell Mediated Immune Responses. Emerg Microbes Infect. 2022 Nov 25:1-13. doi: 10.1080/22221751.2022.2152388. Epub ahead of print. PMID: 36426608.en_US
dc.identifier.eissn2222-1751
dc.identifier.doi10.1080/22221751.2022.2152388en_US
dc.identifier.pmid36426608
dc.identifier.urihttp://hdl.handle.net/20.500.14038/51431
dc.description.abstract­­­­­­In our previous studies, we showed the high immunogenicity of heterologous DNA prime, protein boost HIV vaccines in humans. More recently a combination DNA/Protein COVID-19 vaccine developed by us showed high immunogenicity and sterilizing protection in a non-human primate model against SARS-CoV-2 challenge. In the current study, we aim to test whether this combination DNA/Protein vaccine can also be used as a booster to other types of COVID-19 vaccines.en_US
dc.language.isoenen_US
dc.relation.ispartofEmerging Microbes and Infectionsen_US
dc.relation.urlhttps://doi.org/10.1080/22221751.2022.2152388en_US
dc.rights© 2022 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group, on behalf of Shanghai Shangyixun Cultural Communication Co., Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.en_US
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subjectDNA vaccineen_US
dc.subjectSARS-CoV-2en_US
dc.subjectT cellsen_US
dc.subjectantibodyen_US
dc.subjectheterologous prime – boosten_US
dc.subjectprotein vaccineen_US
dc.titleMouse Study of Combined DNA/Protein COVID-19 Vaccine to Boost High Levels of Antibody and Cell Mediated Immune Responsesen_US
dc.typeAccepted Manuscripten_US
dc.source.journaltitleEmerging microbes & infections
dc.source.beginpage1
dc.source.endpage13
dc.source.countryUnited States
dc.identifier.journalEmerging microbes & infections
refterms.dateFOA2022-12-09T19:52:21Z
dc.contributor.departmentMedicineen_US


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© 2022 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group, on behalf of Shanghai Shangyixun Cultural Communication Co., Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Except where otherwise noted, this item's license is described as © 2022 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group, on behalf of Shanghai Shangyixun Cultural Communication Co., Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.