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Microglia are SYK of Aβ and cell debris

dc.contributor.authorSchafer, Dorothy P
dc.contributor.authorStillman, Jacob M
dc.date.accessioned2022-12-29T20:31:55Z
dc.date.available2022-12-29T20:31:55Z
dc.date.issued2022-10-27
dc.identifier.citationSchafer DP, Stillman JM. Microglia are SYK of Aβ and cell debris. Cell. 2022 Oct 27;185(22):4043-4045. doi: 10.1016/j.cell.2022.09.043. PMID: 36306731.en_US
dc.identifier.eissn1097-4172
dc.identifier.doi10.1016/j.cell.2022.09.043en_US
dc.identifier.pmid36306731
dc.identifier.urihttp://hdl.handle.net/20.500.14038/51504
dc.description.abstractDuring neurodegenerative disease, resident CNS macrophages termed "microglia" assume a neuroprotective role and engulf toxic protein aggregates and cell debris. In this issue of Cell, two groups independently show how spleen tyrosine kinase (SYK) acts downstream of microglial surface receptors to propagate this neuroprotective program in vivo.en_US
dc.language.isoenen_US
dc.relation.ispartofCellen_US
dc.relation.urlhttps://doi.org/10.1016/j.cell.2022.09.043en_US
dc.rightsCopyright © 2022 Elsevier Inc. All rights reserved.en_US
dc.titleMicroglia are SYK of Aβ and cell debrisen_US
dc.typeJournal Articleen_US
dc.source.journaltitleCell
dc.source.volume185
dc.source.issue22
dc.source.beginpage4043
dc.source.endpage4045
dc.source.countryUnited States
dc.identifier.journalCell
dc.contributor.departmentBrudnick Neuropsychiatric Research Instituteen_US
dc.contributor.departmentMorningside Graduate School of Biomedical Sciencesen_US
dc.contributor.departmentNeurobiologyen_US
dc.contributor.departmentSchafer Lab
dc.contributor.studentJacob Stillman
dc.description.thesisprogramNeuroscience


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