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dc.contributor.authorPaolicelli, Rosa C
dc.contributor.authorSierra, Amanda
dc.contributor.authorStevens, Beth
dc.contributor.authorTremblay, Marie-Eve
dc.contributor.authorAguzzi, Adriano
dc.contributor.authorAjami, Bahareh
dc.contributor.authorAmit, Ido
dc.contributor.authorAudinat, Etienne
dc.contributor.authorBechmann, Ingo
dc.contributor.authorBennett, Mariko
dc.contributor.authorBennett, Frederick
dc.contributor.authorBessis, Alain
dc.contributor.authorBiber, Knut
dc.contributor.authorBilbo, Staci
dc.contributor.authorBlurton-Jones, Mathew
dc.contributor.authorBoddeke, Erik
dc.contributor.authorBrites, Dora
dc.contributor.authorBrône, Bert
dc.contributor.authorBrown, Guy C
dc.contributor.authorButovsky, Oleg
dc.contributor.authorCarson, Monica J
dc.contributor.authorCastellano, Bernardo
dc.contributor.authorColonna, Marco
dc.contributor.authorCowley, Sally A
dc.contributor.authorCunningham, Colm
dc.contributor.authorDavalos, Dimitrios
dc.contributor.authorDe Jager, Philip L
dc.contributor.authorde Strooper, Bart
dc.contributor.authorDenes, Adam
dc.contributor.authorEggen, Bart J L
dc.contributor.authorEyo, Ukpong
dc.contributor.authorGalea, Elena
dc.contributor.authorGarel, Sonia
dc.contributor.authorGinhoux, Florent
dc.contributor.authorGlass, Christopher K
dc.contributor.authorGokce, Ozgun
dc.contributor.authorGomez-Nicola, Diego
dc.contributor.authorGonzález, Berta
dc.contributor.authorGordon, Siamon
dc.contributor.authorGraeber, Manuel B
dc.contributor.authorGreenhalgh, Andrew D
dc.contributor.authorGressens, Pierre
dc.contributor.authorGreter, Melanie
dc.contributor.authorGutmann, David H
dc.contributor.authorHaass, Christian
dc.contributor.authorHeneka, Michael T
dc.contributor.authorHeppner, Frank L
dc.contributor.authorHong, Soyon
dc.contributor.authorHume, David A
dc.contributor.authorJung, Steffen
dc.contributor.authorKettenmann, Helmut
dc.contributor.authorKipnis, Jonathan
dc.contributor.authorKoyama, Ryuta
dc.contributor.authorLemke, Greg
dc.contributor.authorLynch, Marina
dc.contributor.authorMajewska, Ania
dc.contributor.authorMalcangio, Marzia
dc.contributor.authorMalm, Tarja
dc.contributor.authorMancuso, Renzo
dc.contributor.authorMasuda, Takahiro
dc.contributor.authorMatteoli, Michela
dc.contributor.authorMcColl, Barry W
dc.contributor.authorMiron, Veronique E
dc.contributor.authorMolofsky, Anna Victoria
dc.contributor.authorMonje, Michelle
dc.contributor.authorMracsko, Eva
dc.contributor.authorNadjar, Agnes
dc.contributor.authorNeher, Jonas J
dc.contributor.authorNeniskyte, Urte
dc.contributor.authorNeumann, Harald
dc.contributor.authorNoda, Mami
dc.contributor.authorPeng, Bo
dc.contributor.authorPeri, Francesca
dc.contributor.authorPerry, V Hugh
dc.contributor.authorPopovich, Phillip G
dc.contributor.authorPridans, Clare
dc.contributor.authorPriller, Josef
dc.contributor.authorPrinz, Marco
dc.contributor.authorRagozzino, Davide
dc.contributor.authorRansohoff, Richard M
dc.contributor.authorSalter, Michael W
dc.contributor.authorSchaefer, Anne
dc.contributor.authorSchafer, Dorothy P
dc.contributor.authorSchwartz, Michal
dc.contributor.authorSimons, Mikael
dc.contributor.authorSmith, Cody J
dc.contributor.authorStreit, Wolfgang J
dc.contributor.authorTay, Tuan Leng
dc.contributor.authorTsai, Li-Huei
dc.contributor.authorVerkhratsky, Alexei
dc.contributor.authorvon Bernhardi, Rommy
dc.contributor.authorWake, Hiroaki
dc.contributor.authorWittamer, Valérie
dc.contributor.authorWolf, Susanne A
dc.contributor.authorWu, Long-Jun
dc.contributor.authorWyss-Coray, Tony
dc.date.accessioned2022-12-29T20:35:30Z
dc.date.available2022-12-29T20:35:30Z
dc.date.issued2022-11-02
dc.identifier.citationPaolicelli RC, Sierra A, Stevens B, Tremblay ME, Aguzzi A, Ajami B, Amit I, Audinat E, Bechmann I, Bennett M, Bennett F, Bessis A, Biber K, Bilbo S, Blurton-Jones M, Boddeke E, Brites D, Brône B, Brown GC, Butovsky O, Carson MJ, Castellano B, Colonna M, Cowley SA, Cunningham C, Davalos D, De Jager PL, de Strooper B, Denes A, Eggen BJL, Eyo U, Galea E, Garel S, Ginhoux F, Glass CK, Gokce O, Gomez-Nicola D, González B, Gordon S, Graeber MB, Greenhalgh AD, Gressens P, Greter M, Gutmann DH, Haass C, Heneka MT, Heppner FL, Hong S, Hume DA, Jung S, Kettenmann H, Kipnis J, Koyama R, Lemke G, Lynch M, Majewska A, Malcangio M, Malm T, Mancuso R, Masuda T, Matteoli M, McColl BW, Miron VE, Molofsky AV, Monje M, Mracsko E, Nadjar A, Neher JJ, Neniskyte U, Neumann H, Noda M, Peng B, Peri F, Perry VH, Popovich PG, Pridans C, Priller J, Prinz M, Ragozzino D, Ransohoff RM, Salter MW, Schaefer A, Schafer DP, Schwartz M, Simons M, Smith CJ, Streit WJ, Tay TL, Tsai LH, Verkhratsky A, von Bernhardi R, Wake H, Wittamer V, Wolf SA, Wu LJ, Wyss-Coray T. Microglia states and nomenclature: A field at its crossroads. Neuron. 2022 Nov 2;110(21):3458-3483. doi: 10.1016/j.neuron.2022.10.020. PMID: 36327895.en_US
dc.identifier.eissn1097-4199
dc.identifier.doi10.1016/j.neuron.2022.10.020en_US
dc.identifier.pmid36327895
dc.identifier.urihttp://hdl.handle.net/20.500.14038/51506
dc.description.abstractMicroglial research has advanced considerably in recent decades yet has been constrained by a rolling series of dichotomies such as "resting versus activated" and "M1 versus M2." This dualistic classification of good or bad microglia is inconsistent with the wide repertoire of microglial states and functions in development, plasticity, aging, and diseases that were elucidated in recent years. New designations continuously arising in an attempt to describe the different microglial states, notably defined using transcriptomics and proteomics, may easily lead to a misleading, although unintentional, coupling of categories and functions. To address these issues, we assembled a group of multidisciplinary experts to discuss our current understanding of microglial states as a dynamic concept and the importance of addressing microglial function. Here, we provide a conceptual framework and recommendations on the use of microglial nomenclature for researchers, reviewers, and editors, which will serve as the foundations for a future white paper.en_US
dc.language.isoenen_US
dc.relation.ispartofNeuronen_US
dc.relation.urlhttps://doi.org/10.1016/j.neuron.2022.10.020en_US
dc.rightsCopyright © 2022 Elsevier Inc. All rights reserved.en_US
dc.titleMicroglia states and nomenclature: A field at its crossroadsen_US
dc.typeJournal Articleen_US
dc.source.journaltitleNeuron
dc.source.volume110
dc.source.issue21
dc.source.beginpage3458
dc.source.endpage3483
dc.source.countryUnited States
dc.identifier.journalNeuron
dc.contributor.departmentBrudnick Neuropsychiatric Research Instituteen_US
dc.contributor.departmentNeurobiologyen_US
dc.contributor.departmentSchafer Lab


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