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dc.contributor.authorZoppo, Christopher T
dc.contributor.authorValero, Daniel Alvarez
dc.contributor.authorMurugan, Venkatesh Arumugam
dc.contributor.authorPavidapha, Alex
dc.contributor.authorFlahive, Julie
dc.contributor.authorNewbury, Alex
dc.contributor.authorFallon, Eleanor
dc.contributor.authorHarman, Aaron
dc.date.accessioned2023-01-24T13:44:39Z
dc.date.available2023-01-24T13:44:39Z
dc.date.issued2022-10-14
dc.identifier.citationZoppo C, Valero DA, Murugan VA, Pavidapha A, Flahive J, Newbury A, Fallon E, Harman A. Splenic Artery Embolization for Unstable Patients with Splenic Injury: A Retrospective Cohort Study. J Vasc Interv Radiol. 2023 Jan;34(1):86-93. doi: 10.1016/j.jvir.2022.10.014. Epub 2022 Oct 14. PMID: 36244633.en_US
dc.identifier.eissn1535-7732
dc.identifier.doi10.1016/j.jvir.2022.10.014en_US
dc.identifier.pmid36244633
dc.identifier.urihttp://hdl.handle.net/20.500.14038/51577
dc.description.abstractPurpose: To compare the outcomes of splenic artery embolization (SAE) for acute splenic injury (ASI) between patients who are hemodynamically stable (HDS) and hemodynamically unstable (HDU). Nonoperative management with SAE has become an accepted practice for patients who are HDS with ASI; however, SAE for the treatment of patients who are HDU with ASI has not been well studied. Materials and methods: A retrospective cohort study was performed, including 52 patients who were HDU and HDS who underwent SAE for ASI at a Level 1 trauma center. HDU was defined as the lowest recorded systolic blood pressure prior to intervention <90 mm Hg. Utilizing the American Association for Surgery of Trauma (AAST) splenic injury scale, AAST Grades 1-3 were defined as low grade, and Grades 4-5 were defined as high grade. The primary outcomes were survival at 30 days and the need for subsequent splenectomy. Results: Seventy-five percent (n = 39) of the patients were HDS, and 25% (n = 13) were HDU. The majority (69%) of patients who were HDU who underwent SAE did not require splenectomy, compared with 95% of patients who were HDS (P = .03). No significant difference in 30-day survival between patients who were HDU and HDS was noted. No major adverse events were recorded. There was no significant difference in 30-day patient survival or the rate of subsequent splenectomy between high-grade and low-grade splenic injuries. Conclusions: In this retrospective cohort study, there was no statistically significant difference in the adverse events or 30-day post-SAE survival rates between patients who were HDS and HDU with ASI. The authors conclude that SAE can be a safe and effective treatment option for patients who are HDU with ASI, including high-grade splenic injury.en_US
dc.language.isoenen_US
dc.relation.ispartofJournal of Vascular and Interventional Radiologyen_US
dc.relation.urlhttps://doi.org/10.1016/j.jvir.2022.10.014en_US
dc.rightsCopyright © 2022 SIR. Published by Elsevier Inc. All rights reserved.en_US
dc.titleSplenic Artery Embolization for Unstable Patients with Splenic Injury: A Retrospective Cohort Studyen_US
dc.typeJournal Articleen_US
dc.source.journaltitleJournal of vascular and interventional radiology : JVIR
dc.source.volume34
dc.source.issue1
dc.source.beginpage86
dc.source.endpage93
dc.source.countryUnited States
dc.identifier.journalJournal of vascular and interventional radiology : JVIR
dc.contributor.departmentRadiologyen_US
dc.contributor.departmentT.H. Chan School of Medicineen_US
dc.contributor.departmentBiostatistics and Health Services Researchen_US


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