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Except where otherwise noted, this item's license is described as © 2022 van ‘t Spijker et al. This article is distributed exclusively by the RNA Society for the first 12 months after the full-issue publication date (see http://rnajournal.cshlp.org/site/misc/terms.xhtml). After 12 months, it is available under a Creative Commons License (Attribu- tion-NonCommercial 4.0 International), as described at http:// creativecommons.org/licenses/by-nc/4.0/.