The curious case of a cryptic Cryptosporidium and a missing dendritic cell subset
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Donguk LeeDocument Type
Journal ArticlePublication Date
2021-12-22
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Animal models for studying immune responses to Cryptosporidium, a parasite that causes gastrointestinal disease, have been a challenge due to the parasite's poor infectivity in mice. Russler-Germain et al. discovered a 'commensal' strain of Cryptosporidium, capable of stable infection and vertical transmission, that elicits a T helper type 1 (Th1) response to promote intestinal homeostasis.Source
Lee D, Huseby ES, Gowthaman U. The curious case of a cryptic Cryptosporidium and a missing dendritic cell subset. Trends Parasitol. 2022 Feb;38(2):101-103. doi: 10.1016/j.pt.2021.12.003. Epub 2021 Dec 22. PMID: 34953724; PMCID: PMC9576149.DOI
10.1016/j.pt.2021.12.003Permanent Link to this Item
http://hdl.handle.net/20.500.14038/51997PubMed ID
34953724Rights
Copyright © 2021 Elsevier Ltd. All rights reserved.ae974a485f413a2113503eed53cd6c53
10.1016/j.pt.2021.12.003