Phosphaturic mesenchymal tumor: two cases highlighting differences in clinical and radiologic presentation
Student AuthorsConnie Ge
UMass Chan AffiliationsOrthopedics and Physical Rehabilitation
T.H. Chan School of Medicine
Document TypeCase Report
Phosphaturic mesenchymal tumor
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AbstractPhosphaturic mesenchymal tumors are rare, usually benign neoplasms that occur in the soft tissue or bone and are the cause of nearly all cases of tumor-induced osteomalacia. Tumor-induced osteomalacia due to phosphaturic mesenchymal tumor is a challenging diagnosis to make-patients present with variable clinical and radiologic findings and the culprit neoplasm is often small and can occur anywhere head to toe. We present two cases of phosphaturic mesenchymal tumor in the scapular body and plantar foot. In both cases, the patient endured years of debilitating symptoms before a tissue diagnosis was eventually reached. Descriptions of clinical presentation, laboratory workup, surgical resection, and imaging characteristics, with a focus on CT, MRI, and functional imaging, are provided to assist with the diagnosis and management of this rare entity. A brief review of current literature and discussion of the differential diagnoses of phosphaturic mesenchymal tumor is also provided.
SourceGu J, Ge C, Joshi G, Most M, Tai R. Phosphaturic mesenchymal tumor: two cases highlighting differences in clinical and radiologic presentation. Skeletal Radiol. 2023 Oct 4. doi: 10.1007/s00256-023-04462-w. Epub ahead of print. PMID: 37792035.
Permanent Link to this Itemhttp://hdl.handle.net/20.500.14038/52772
Rights© 2023. The Author(s), under exclusive licence to International Skeletal Society (ISS).