McDermott, Mary McGraeReed, George W.Greenland, PhilipMazor, Kathleen M.Pagoto, Sherry L.Ockene, Judith K.Graff, RexMerriam, Philip A.Leung, KatherineManheim, LarryKibbe, Melina R.Olendzki, Barbara C.Pearce, William H.Ockene, Ira S.2022-08-232022-08-232011-06-252011-10-27Am J Med. 2011 Jun;124(6):557-65. <a href="http://dx.doi.org/10.1016/j.amjmed.2010.11.032" target="_blank">Link to article on publisher's site</a>0002-9343 (Linking)10.1016/j.amjmed.2010.11.03221605733https://hdl.handle.net/20.500.14038/44736BACKGROUND: Peripheral arterial disease patients are less likely than other high-risk patients to achieve ideal low-density lipoprotein (LDL) cholesterol levels. This randomized controlled trial assessed whether a telephone counseling intervention, designed to help peripheral arterial disease patients request more intensive cholesterol-lowering therapy from their physician, achieved lower LDL cholesterol levels than 2 control conditions. METHODS: There were 355 peripheral arterial disease participants with baseline LDL cholesterol >/=70 mg/dL enrolled. The primary outcome was change in LDL cholesterol level at 12-month follow-up. There were 3 parallel arms: telephone counseling intervention, attention control condition, and usual care. The intervention consisted of patient-centered counseling, delivered every 6 weeks, encouraging participants to request increases in cholesterol-lowering therapy from their physician. The attention control condition consisted of telephone calls every 6 weeks providing information only. The usual care condition participated in baseline and follow-up testing. RESULTS: At 12-month follow-up, participants in the intervention improved their LDL cholesterol level, compared with those in attention control (-18.4 mg/dL vs -6.8 mg/dL, P=.010) but not compared with those in usual care (-18.4 mg/dL vs -11.1 mg/dL, P=.208). Intervention participants were more likely to start a cholesterol-lowering medication or increase their cholesterol-lowering medication dose than those in the attention control (54% vs 18%, P=.001) and usual care (54% vs 31%, P CONCLUSION: Telephone counseling that helped peripheral arterial disease patients request more intensive cholesterol-lowering therapy from their physician achieved greater LDL cholesterol decreases than an attention control arm that provided health information alone.en-USAdultAgedAnticholesteremic AgentsCholesterol, LDL*CounselingFemaleFollow-Up StudiesHumansHydroxymethylglutaryl-CoA Reductase InhibitorsHypercholesterolemiaMaleMiddle AgedPeripheral Arterial DiseaseTelephoneTime FactorsTreatment OutcomeUMCCTS fundingBehavioral Disciplines and ActivitiesBehavior and Behavior MechanismsCardiovascular DiseasesCommunity Health and Preventive MedicinePreventive MedicineJournal Articlehttps://escholarship.umassmed.edu/prevbeh_pp/1572316503prevbeh_pp/157