Davaro, Raul E.Cheeseman, Sarah H.Keroack, Mark A.Ellison, Richard T. III2022-08-232022-08-231996-07-012015-12-23Davaro RE, Cheeseman SH, Keroack MA, Ellison RT III. The significance of isolated anti-HBc seropositivity in patients infected with HIV. Clin Infect Dis 1996;23:189-190. doi: 10.1093/clinids/23.1.189. <a href="http://dx.doi.org/10.1093/clinids/23.1.189">Link to article on publisher's site</a>10.1093/clinids/23.1.189https://hdl.handle.net/20.500.14038/35007To decrease transmission of hepatitis B virus (HBV), immunization with the HBV vaccine has been recommended for individuals in high-risk populations who are seronegative for antibodies to hepatitis B [1]. Isolated antibody to hepatitis B core antigen (antiHBc) seropositivity is found in about 2.5% of volunteer blood donors in the United States and is often considered a false-positive serological response [2]. However, in a retrospective review of HIV-infected patients in Worcester, Massachusetts, we unexpectedly noted isolated anti-HBc seropositivity in > 30% of our population. To gain insight into the meaning of the isolated anti-HBc seropositivity, we further analyzed this patient population.en-USImmunityImmunology of Infectious DiseaseInfectious DiseaseJournal Articlehttps://escholarship.umassmed.edu/infdis_pp/2257972081infdis_pp/225