Gounis, Matthew JWakhloo, Ajay K.Chueh, Juyu2022-08-232022-08-232013-06-052014-05-13Gounis MJ, Wakhloo AK, Chueh JY. Preclinical investigations for thrombectomy devices--does it translate to humans? Stroke. 2013 Jun;44(6 Suppl 1):S7-S10. doi: 10.1161/STROKEAHA.111.000692. <a href="http://dx.doi.org/10.1161/STROKEAHA.111.000692">Link to article on publisher's site</a>0039-2499 (Linking)10.1161/STROKEAHA.111.00069223709736https://hdl.handle.net/20.500.14038/30170Currently, most preclinical models to validate thrombectomy technologies have not directly translated to the clinical arena. Herein, we review our strategy that combines in vitro and in vivo modeling to assess thrombectomy device safety and efficacy quantitatively.en-USAngiography, Digital SubtractionAnimalsCerebral AngiographyCerebrovascular CirculationDevice ApprovalDisease Models, AnimalDogsFemaleHumansMaleMicroscopy, Electron, ScanningModels, AnatomicSafetyStrokeThrombectomyUnited StatesUnited States Food and Drug AdministrationAcute ischemic strokeclotembolic showerpreclinical modelingrecanalizationthrombectomyCardiovascular DiseasesNervous System DiseasesNeurologyRadiologySurgical Procedures, OperativeJournal Articlehttps://escholarship.umassmed.edu/faculty_pubs/4125574396faculty_pubs/412