Singh, RheaCohen, Jay LAstudillo, MichaelHarris, John EFreeman, Esther E2023-11-062023-11-062022-06-20Singh R, Cohen JL, Astudillo M, Harris JE, Freeman EE. Vitiligo of the arm after COVID-19 vaccination. JAAD Case Rep. 2022 Oct;28:142-144. doi: 10.1016/j.jdcr.2022.06.003. Epub 2022 Jun 20. PMID: 35756074; PMCID: PMC9213010.2352-512610.1016/j.jdcr.2022.06.00335756074https://hdl.handle.net/20.500.14038/52699As we head into the third year of the COVID-19 pandemic and second year of COVID-19 vaccine availability, cutaneous reactions to COVID-19 and various COVID-19 vaccine types have become increasingly reported and categorized. The American Academy of Dermatology and International League of Dermatological Societies have collaborated to create a COVID-19 dermatology registry to record cases of cutaneous reactions associated with either the infection or the vaccine. The most common cutaneous reactions seen after COVID-19 vaccination are local injection site reactions. There have been limited reports of vitiligo after COVID-19 vaccination to date, and literature remains scarce. Clinical trials of COVID-19 vaccines did not report any cases of new-onset vitiligo after mRNA vaccines; however, there was 1 case after adenovirus-based AstraZeneca vaccination among the cutaneous adverse events noted after vaccination. Here, we present a case of a patient developing vitiligo specifically on the arm at the site of injection after COVID-19 vaccination.enCopyright 2022 Published by Elsevier on behalf of the American Academy of Dermatology, Inc. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc- nd/4.0/).Attribution-NonCommercial-NoDerivatives 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-nd/4.0/COVID-19SARS-CoV-2depigmentationvaccinesvitiligoCase ReportJAAD case reports