Atianand, Maninjay K.Fitzgerald, Katherine A2022-08-232022-08-232016-03-042017-03-07Science. 2016 Mar 4;351(6277):1032. doi: 10.1126/science.aaf4691. <a href="https://doi.org/10.1126/science.aaf4691">Link to article on publisher's site</a>0036-8075 (Linking)10.1126/science.aaf469126941307https://hdl.handle.net/20.500.14038/28921T helper lymphocytes play essential roles in the adaptive immune system. They come in distinct types defined by unique transcriptional programs that control their development and functions. Among these, T helper 17 (TH17) cells are important in protecting mucosal surfaces against fungal and bacterial infections. In addition, TH17 cells contribute to the pathogenesis of multiple autoimmune diseases (1). A recent study (2) adds yet another layer of complexity to the biology of these complex cells—an RNA helicase and a long noncoding RNA (lncRNA) that act together to control their effector functions.en-USImmunology and Infectious DiseaseJournal Articlehttps://escholarship.umassmed.edu/faculty_pubs/11509801463faculty_pubs/1150